Heat Shock-Binding Protein 21 Regulates the Innate Immune Response to Viral Infection

Author:

Xu Yan1,Yang Qiong1,Xue Binbin1,Wang Xintao1,Tian Renyun1,Deng Rilin1,Chen Shengwen1,Wang Xiaohong1,Wang Luoling1,Wang Cong1,Chen Jinwen1,You Ruina1,Liu Qian1,Li Huiyi1,Wang Jingjing1,Li Xinran1,Liu Shun1,Yang Di1,Tang Songqing1,Zhu Haizhen12ORCID

Affiliation:

1. Institute of Pathogen Biology and Immunology of College of Biology, Hunan Provincial Key Laboratory of Medical Virology, State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Changsha, China

2. Research Center of Cancer Prevention and Treatment, Translational Medicine Research Center of Liver Cancer, Hunan Cancer Hospital, Changsha, China

Abstract

The innate immune system is the first-line host defense against microbial pathogen invasion. The physiological functions of molecular chaperones, involving cell differentiation, migration, proliferation and inflammation, have been intensively studied.

Funder

Hunan Natural Science Foundation

National Natural Science Foundation of China

National Science and Technology Major Project

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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