Author:
Trowsdale J,Anagnostopoulos C
Abstract
It was previously shown that in strains of Bacillus subtilis bearing the trpE26 mutation a chromosome segment (from trpD to ilvA) is translocated to a position near the thr region. Further PBS1-mediated transduction data have now revealed that these strains also possess an inversion of part of the chromosome from the origin of replication, down to the tre locus on one side and the cysB locus on the other. These data concern evidence of linkage of tre-12- to markers in the translocation (hisH2, tyrA1, and metB3) as well as linkage of the cysB3 marker to thi-86, gly-133, and catA. They explain the previously observed absence of linkage of markers in the translocated segment to cysB3. The model proposed for the formation of merodiploids in trpE26 strains, which calls for the fusion of two genetic elements, is not incompatible with this new finding.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference14 articles.
1. Genetic studies relating to the production of transformed clones diploid in the tryptophan region of the Bacillus subtilis genome;Audit C.;J. Bacteriol.,1973
2. Audit C. and C. Anagnostopoulos. 1972. Production of stable and persistent unstable heterogenotes in a mutant ofBacillus subtilis p. 117-125. In H. 0. Halvorson R. Hanson and L. L. Campbell (ed.) Spores V. American Society for Microbiology Washington D.C.
3. Studies on the size of the diploid region in Bacillus subtilis merozygotes from strains carrying the trpE26 mutation;Audit C.;Mol. Gen. Genet.,1975
4. Induced biochemical mutations in Bacillus subtilis;Burkholder P. R.;Am. J. Bot.,1947
5. Bidirectional chromosome replication in BaciUus subtilis 168;Harford N.;J. Bacteriol.,1975
Cited by
18 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献