Appearance of enzyme activities catalyzing conversion of sterigmatocystin to aflatoxin B1 in late-growth-phase Aspergillus parasiticus cultures-Reference-Cited by-同舟云学术

Appearance of enzyme activities catalyzing conversion of sterigmatocystin to aflatoxin B1 in late-growth-phase Aspergillus parasiticus cultures

Published:1987-07 Issue:7 Volume:53 Page:1711-1713
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Cleveland T E¹,Lax A R¹,Lee L S¹,Bhatnagar D¹

Affiliation:

1. Southern Regional Research Center, U.S. Department of Agriculture, New Orleans, Louisiana 70179.

Abstract

Two activities involved in terminal pathway conversion of sterigmatocystin to aflatoxin B1 were isolated from an aflatoxin-nonproducing mutant of Aspergillus parasiticus (avn-1), and the time course of appearance of the activities in culture was determined. Subcellular fractionation of fungal mycelia resolved the two activities into a postmicrosomal activity which catalyzed conversion of sterigmatocystin to O-methylsterigmatocystin and a microsomal activity which converted O-methylsterigmatocystin to aflatoxin B1. The two activities were absent in 24-h-old cells, increased to optimum levels during the stationary phase, and then declined.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/aem.53.7.1711-1713.1987

Reference25 articles.

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5. Identification of O-methylsterigmatocystin as an aflatoxin Bl/G, precursor in Aspergillus parasiticus;Bhatnagar D.;Appl. Environ. Microbiol.,1987

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