Abstract
The incorporation of various potential intermediates into versicolorin A by a versicolorin A-accumulating mutant of Aspergillus parasiticus was studied. Both whole mycelium and cell-free extracts of this mutant were able to convert 14C-labeled versiconal hemiacetal acetate to versicolorin A. By the use of a labeled double substrate technique it was shown that two other compounds, versicolorin A hemiacetal and its acetate derivative, were also converted to versicolorin A. It is concluded that one or both of these compounds are intermediates in the biosynthesis of versicolorin A and therefore may possibly be involved in the biogenesis of the aflatoxins.
Publisher
American Society for Microbiology
Subject
Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology
Reference15 articles.
1. The use of cell free extracts derived from fungal protoplasts in the study of aflatoxin biosynthesis;Anderson M. S.;Experientia,1979
2. Reduction of sterigmatocystin and versicolorin A hemiacetals with sodium borohydride;Chen P. N.;J. Org. Chem.,1977
3. The use of fungal protoplasts in the study of aflatoxin biosynthesis;Dutton ML F;Experientia,1978
4. The inhibition of aflatoxin biosynthesis by organophosphorous compounds;Dutton M. F.;J. Food Protection,1980
5. Dutton M. F. and J. G. Heathcote. 1968. The structure biochemical properties and origins of the aflatoxins B2. and G2.. Chem. Ind. (London) 30 March:418-421.
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