Kinetics of Bacterial Inactivation by Peroxynitric Acid in the Presence of Organic Contaminants-Reference-Cited by-同舟云学术

Kinetics of Bacterial Inactivation by Peroxynitric Acid in the Presence of Organic Contaminants

Published:2021-01-04 Issue:2 Volume:87 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Yokoyama Takashi¹^ORCID,Miyazaki Shinya¹,Akagi Hiroko¹,Ikawa Satoshi²,Kitano Katsuhisa¹

Affiliation:

1. Center for Atomic and Molecular Technologies, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan

2. Osaka Research Institute of Industrial Science and Technology, Izumi, Osaka, Japan

Abstract

A good disinfectant for the human body should have various properties, such as strong bactericidal activity, harmlessness to living tissues, and resistance against biological fluids (or other organic contaminants). Peroxynitric acid (PNA) showed a bactericidal effect that was several tens up to several hundred times higher per unit of molarity than that of sodium hypochlorite and peracetic acid, which are used as general disinfectants for medical equipment. Moreover, the high resistance of PNA to organic load was confirmed, indicating that PNA will inactivate bacteria effectively even on contaminated surfaces, such as used medical devices or the human body surface. Therefore, we propose that PNA can be used as a strong disinfectant for the human body.

Funder

MEXT | Japan Society for the Promotion of Science

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.01860-20

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