Prototype of a Fully Automated Device for Determination of Bacterial Antibiotic Susceptibility in the Clinical Laboratory

Author:

Isenberg Henry D.12,Reichler Allen12,Wiseman Donald12

Affiliation:

1. The Long Island Jewish Medical Center, New Hyde Park, New York 11040

2. Technicon Instrument Corp., Tarrytown, New York 10591

Abstract

A completely automated system for the performance of antibiotic susceptibility tests in the clinical laboratory is described. With a modicum of personnel involvement, data on 40 specimens tested against 13 antibiotics are obtained every hour after an initial 3-hr period. The step by step explanation of the functioning of this prototype system, based on a thoroughly tested manual model, is presented. The system compares well with the standard diffusion test and has a potential for application to other endeavors of the clinical microbiology laboratory with a comparable saving in time and labor.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference12 articles.

1. Barber M. and L. P. Garrod. 1963. Antibiotic and chemotherapy. The Williams & Wilkins Co. Baltimore.

2. Antibiotic susceptibility testing by a standardized single disc method;Bauer A. W.;Amer. J. Clin. Pathol.,1966

3. Rational use of antibiotics in hospitals. Scand;Ericsson H.;J. Clin. Lab. Invest. 12(Suppl. 50).,1960

4. Ericsson H. 1964. Standardization of methods for conducting microbic sensitivity tests. Preliminary Report of a Working Group of the International Collaborative Study Sponsored by WHO. Karolinska siukhuset Stockholm.

5. Ericsson H. and J. C. Sherris. 1971. Antibiotic sensitivity testing. Report of an international collaborative study. Acta Pathol. Microbiol. Scand. Sec. B 79(Suppl. 217).

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