Effect of Relative Humidity on Formaldehyde Decontamination

Author:

Spiner David R.1,Hoffman Robert K.1

Affiliation:

1. Commodity Development and Engineering Laboratories, U.S. Army Biological Defense Research Center, Fort Detrick, Frederick, Maryland 21701

Abstract

Death rate studies were conducted to determine the effect of varying the concentration, humidity, and type of surface on the sporicidal activity of formaldehyde gas. Washed and unwashed spores were similarly exposed to detect the influence of residual nutrient growth medium upon the rate of kill. The results indicated that the sporicidal activity of formaldehyde gas varies directly with its concentration. Relative humidities (RH) over 50% proved essential for sterility. Spores on a porous surface (cotton cloth) were more readily killed at lower RH than those on a nonporous surface (glass). The reverse occurred at very high RH. At 75% RH, the unwashed spores on glass were killed faster than the washed spores.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference7 articles.

1. Adsorption of formaldehyde by various surfaces during gaseous decontamination;Braswell J. R.;Appl. Microbiol.,1970

2. Disinfection of fabrics with gaseous formaldehyde;Committee on Formaldehyde Disinfection.;J. Hyg.,1958

3. Effect of relative humidity on the penetrability and sporicidal activity of formaldehyde;Hoffman R. K.;Appl. Microbiol.,1970

4. A method for testing self-disinfecting surfaces;Hoffman R. K.;Soap Chem. Spec.,1955

5. Investigation on the sterilization efficiency of gaseous formaldehyde;Nordgren G.;Acta Pathol. Microbiol. Scand. Suppl.,1939

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