Correlation Between Growth Inhibition and the Binding of Various Penicillins and Cephalosporins to Staphylococcus aureus-Reference-Cited by-同舟云学术

Correlation Between Growth Inhibition and the Binding of Various Penicillins and Cephalosporins to Staphylococcus aureus

Published:1969-08 Issue:2 Volume:99 Page:459-462
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Edwards John R.¹,Park James T.¹

Affiliation:

1. Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts 02111

Abstract

The concentration of penicillin (or cephalosporin) required to achieve a given rate of binding to Staphylococcus aureus H correlates well with that required for inhibition of growth. This result suggests that the irreversible binding of penicillins and cephalosporins to cells is responsible for their biological activity.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jb.99.2.459-462.1969

Reference16 articles.

1. Biosynthesis of cell wall mucopeptide by a particulate fraction from Staphylococcus aureus;Chatterjee A. N.;Proc. Nat. Acad. Sci. U.S.A.,1964

2. The association of the penicillin-binding component of staphylococcus with a lipid fraction;Cooper P. D.;J. Gen. Microbiol.,1954

3. The site of action of penicillin: some properties of the penicillin-binding component of Staphylococcus aureus;Cooper P. D.;J. Gen. Microbiol.,1955

4. Site of action of radiopenicillin;Cooper P. D.;Bacteriol. Rev.,1956

5. A note on the use of radioactive penicillin;Cooper P. D.;J. Gen. Microbiol.,1954

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