A reevaluation of the higher taxonomy of viruses based on RNA polymerases

Author:

Zanotto P M1,Gibbs M J1,Gould E A1,Holmes E C1

Affiliation:

1. Natural Environment Research Council, Institute of Virology and Environmental Microbiology, Oxford, United Kingdom.

Abstract

In order to assess the validity of classifications of RNA viruses, published alignments and phylogenies of RNA-dependent RNA and DNA polymerase sequences were reevaluated by a Monte Carlo randomization procedure, bootstrap resampling, and phylogenetic signal analysis. Although clear relationships between some viral taxa were identified, overall the sequence similarities and phylogenetic signals were insufficient to support many of the proposed evolutionary groupings of RNA viruses. Likewise, no support for the common ancestry of RNA-dependent RNA polymerases and reverse transcriptases was found.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Reference24 articles.

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