Metabolic Disposition of 2, 4, 6-Trinitrotoluene

Author:

Won William D.12,Heckly Robert J.12,Glover Donald J.12,Hoffsommer John C.12

Affiliation:

1. Naval Biomedical Research Laboratory, School of Public Health, University of California, Berkeley, California 94720

2. Naval Ordnance Laboratory, White Oak, Silver Spring, Maryland 20910

Abstract

Three pseudomonas-like organisms have been shown to metabolically oxidize 2, 4, 6-trinitrotoluene (TNT). Capability for this oxidative dissimilation varied with each organism. Of the three, isolate “Y” was the most proficient, isolate “I” was less, and isolate “II” was the least. For accelerated TNT degradation, addition of glucose or a nitrogenous substance was essential. Complete dissimilation within 24 h by isolate “Y” cultures supplemented with 0.5% yeast extract is presumed since no TNT was detectable.

Publisher

American Society for Microbiology

Subject

General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference4 articles.

1. The metabolism of 2:4: 6-trinitrotoluene (a-TNT);Channon H. J.;Biochem. J.,1944

2. Mathews E. R. E. H. Tex R. L. Taylor and J. F. Newell. 1954. Laboratory studies pertaining to the treatment of TNT wastes. Paper presented to Division of Water Sewage and Sanitation Chemistry 126th Meeting American Chemical Society New York N.Y.

3. Sax N. I. 1957. Dangerous Properties of Industrial Materials. Rheinhold Publ. Corp. New York N.Y.

4. Umbreit W. W. R. H. Burris and J. F. Stauffer. 1957. Manometric and biochemical techniques 3rd ed. Burgess Publishing Co. Minneapolis Minn.

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