Extensive Genetic Diversity and Widespread Azole Resistance in Greenhouse Populations of Aspergillus fumigatus in Yunnan, China

Author:

Zhou Duanyong1234,Korfanty Greg A.5,Mo Meizi124,Wang Ruirui124,Li Xiao124,Li Haixia124,Li Shuoshuo124,Wu Jin-Yan6,Zhang Ke-Qin14,Zhang Ying14,Xu Jianping154ORCID

Affiliation:

1. State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Yunnan University, Kunming, People’s Republic of China

2. College of Life Science, Yunnan University, Kunming, People’s Republic of China

3. School of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi, People’s Republic of China

4. Key Laboratory for Southwest Microbial Diversity of the Ministry of Education, Yunnan University, Kunming, People’s Republic of China

5. Department of Biology, McMaster University, Hamilton, Ontario, Canada

6. Public Research Laboratory, Hainan Medical University, Haikou, People’s Republic of China

Abstract

The origin and prevalence of azole-resistant Aspergillus fumigatus have been attracting increasing attention from biologists, clinicians, and public health agencies. Current evidence suggests agricultural fungicide use as a major cause.

Funder

Global Science Initiative of McMaster University

Science and Technology for Young Talents

National Natural Science Foundation of China

Natural Science Foundation of Hainan Province

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

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