In Vitro Susceptibilities of Isolates of Sporothrix schenckii to Itraconazole and Terbinafine-Reference-Cited by-同舟云学术

In Vitro Susceptibilities of Isolates of Sporothrix schenckii to Itraconazole and Terbinafine

Published:2004-09 Issue:9 Volume:42 Page:4319-4320
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Kohler Lidiane Meire¹,Monteiro Paulo César Fialho²,Hahn Rosane Christine¹,Hamdan Júnia Soares¹

Affiliation:

1. Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais

2. Instituto de Pesquisa Clínica Evandro Chagas, Fundação Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil

Abstract

ABSTRACT Thirty isolates of the yeast form of Sporothrix schenckii were evaluated for in vitro susceptibility to itraconazole and terbinafine by the recommended NCCLS modified technique (M27-A2). The MICs of itraconazole obtained oscillated between 0.062 and 4.0 μg/ml, and those of terbinafine oscillated between 0.007 and 0.50 μg/ml; therefore, terbinafine showed greater in vitro activity.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.42.9.4319-4320.2004

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