Affiliation:
1. Twinbrook II Research Facility, National Institute of Allergy and Infectious Diseases, Rockville, Maryland 20852.
Abstract
Prior exposure (priming) of BALB/cByJ mice to a low dose of lipopolysaccharide derived from Escherichia coli 055 or Serratia marcescens, followed by immunization with an optimally immunogenic dose of the same lipopolysaccharide 2 to 30 days later, results in the expression of substantially reduced antibody responses. Such unresponsiveness, which is antigen specific, occurs in a cyclic manner with time after priming.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference20 articles.
1. Regulation of the antibody response to pneumococcal polysaccharide by thymus-derived cells;Baker P. J.;Rev. Infect. Dis.,1981
2. Cyclic development of immunological memory to bacterial lipopolysaccharide;Baker P. J.;Infect. Immun.,1985
3. Quantitative and qualitative studies on the primary antibody response to pneumococcal polysaccharide at the cellular level;Baker P. J.;J. Immunol.,1969
4. U se of erythrocytes sensitized with purified pneumococcal polysaccharides for the assay of antibody and antibody-producing cells;Baker P. J.;Appl. Microbiol.,1969
5. Persistence of immunogenicity of two complex antigens retained in vivo;Britton S.;Immunology,1968
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