First Isolation of Vancomycin-Resistant Enterococcus faecium Carrying Plasmid-Borne <i>vanD1</i>-Reference-Cited by-同舟云学术

First Isolation of Vancomycin-Resistant Enterococcus faecium Carrying Plasmid-Borne vanD1

Published:2022-11-15 Issue:11 Volume:66 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Hisatsune Junzo¹²³,Tanimoto Koichi⁴,Kohara Tadahiro³⁵,Myoken Yoshinari⁵,Tomita Yoshiharu⁴⁶^ORCID,Sugai Motoyuki¹²³^ORCID

Affiliation:

1. Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Higashimurayama, Tokyo, Japan

2. Department of Antimicrobial Resistance, Hiroshima University Graduate School of Biomedical & Health Sciences, Hiroshima, Japan

3. Hiroshima University Project Research Center for Nosocomial Infectious Diseases, Hiroshima, Japan

4. Laboratory of Bacterial Drug Resistance, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan

5. Department of Oral Surgery, Hiroshima Red Cross and Atomic-bomb Survivors Hospital, Hiroshima, Japan

6. Department of Bacteriology, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan

Abstract

Vancomycin-resistant Enterococcus faecium carrying the vanD1 gene on plasmid pEF-D was isolated from a fecal sample of a hospitalized patient in Japan. The strain JH5687 showed moderate resistance to vancomycin (MIC, 16 μg/mL) but remained susceptible to teicoplanin (MIC, 1 μg/mL).

Funder

Japan Agency for Medical Research and Development

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/aac.01029-22

Reference26 articles.

1. Enterococcus faecium N03-0072 carries a new VanD-type vancomycin resistance determinant: characterization of the VanD5 operon

2. Characterization of the vanD Glycopeptide Resistance Gene Cluster from Enterococcus faecium BM4339

3. Molecular Characterization of the vanD Gene Cluster and a Novel Insertion Element in a Vancomycin-Resistant Enterococcus Isolated in Canada