Multicenter Clinical Evaluation of the Automated Aries Group A Strep PCR Assay from Throat Swabs

Author:

Kanwar N.1,Crawford J.1,Ulen C.2,Uphoff T. S.3,Dien Bard J.4,Dunn R.5,Drain A.5,Selvarangan R.1

Affiliation:

1. Department of Pathology and Laboratory Medicine, Children’s Mercy Hospital and Clinics, Kansas City, Missouri, USA

2. Advanced Pediatrics, Vienna, Virginia, USA

3. Marshfield Clinic, Marshfield, Wisconsin, USA

4. Children’s Hospital Los Angeles, Los Angeles, California, USA

5. Luminex Corporation, Austin, Texas, USA

Abstract

Group A Streptococcus (GAS) is one of the leading causes of bacterial pharyngitis. Early GAS diagnosis is critical for appropriate antibiotic administration that reduces the risk of GAS sequelae and limits spread of the infection.

Funder

Luminex Corporation

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference28 articles.

1. Efstratiou A, Lamagni T. 2016. Epidemiology of Streptococcus pyogenes, p 601–627. In Ferretti JJ, Stevens DL, Fischetti VA (ed), Streptococcus pyogenes: basic biology to clinical manifestations. University of Oklahoma Health Sciences Center, Oklahoma City, OK.

2. Ambulatory medical care utilization estimates for 2007;Schappert SM;Vital Health Stat,2011

3. The global burden of group A streptococcal diseases

4. Sanyahumbi A, Colquhoun S, Wyber R, Carapetis J. 2016. Global disease burden of group A Streptococcus, p 661–704. In Ferretti JJ, Stevens DL, Fischetti VA (ed), Streptococcus pyogenes: basic biology to clinical manifestations. University of Oklahoma Health Sciences Center, Oklahoma City, OK.

5. Clinical practice guideline for the diagnosis and management of group A streptococcal pharyngitis: 2012 update by the Infectious Diseases Society of America;Shulman S;Clin Infect Dis,2014

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