Multicenter Clinical Evaluation of the Revogene Strep A Molecular Assay for Detection of Streptococcus pyogenes from Throat Swab Specimens

Author:

Banerjee D.1,Michael J.1,Schmitt B.2,Salimnia H.3,Mhaissen N.4,Goldfarb D. M.5,Lachance P.6,Faron M. L.7,Aufderheide T.7,Ledeboer N.7,Weissfeld A.8,Selvarangan R.1

Affiliation:

1. Children’s Mercy Hospital, Kansas City, Missouri, USA

2. Indiana University School of Medicine, Indianapolis, Indiana, USA

3. Wayne State University School of Medicine, Detroit, Michigan, USA

4. Valley Children’s Hospital, Fresno, California, USA

5. BC Children’s and Women’s Hospital, Vancouver, British Columbia, Canada

6. Centre de Recherche Saint-Louis, Quebec City, Canada

7. Medical College of Wisconsin, Milwaukee, Wisconsin, USA

8. Microbiology Specialists Inc., Houston, Texas, USA

Abstract

Group A streptococcus (GAS) species cause bacterial pharyngitis in both adults and children. Early and accurate diagnosis of GAS is important for appropriate antibiotic therapy to prevent GAS sequalae. The Revogene Strep A molecular assay (Meridian Bioscience Canada Inc, Quebec City, QC, Canada) is an automated real-time PCR assay for GAS detection from throat swab specimens within approximately 70 min. This multicenter prospective study evaluated the performance of the Revogene Strep A molecular assay compared to that of bacterial culture.

Funder

Meridian Bioscience Canada Inc

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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