A Toxic Environment: a Growing Understanding of How Microbial Communities Affect Escherichia coli O157:H7 Shiga Toxin Expression-Reference-Cited by-同舟云学术

A Toxic Environment: a Growing Understanding of How Microbial Communities Affect Escherichia coli O157:H7 Shiga Toxin Expression

Published:2020-11-24 Issue:24 Volume:86 Page:
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Nawrocki Erin M.¹,Mosso Hillary M.²,Dudley Edward G.¹³^ORCID

Affiliation:

1. Department of Food Science, The Pennsylvania State University, University Park, Pennsylvania, USA

2. The Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, Pennsylvania, USA

3. E. coli Reference Center, The Pennsylvania State University, University Park, Pennsylvania, USA

Abstract

Enterohemorrhagic Escherichia coli (EHEC) strains, including E. coli O157:H7, cause severe illness in humans due to the production of Shiga toxin (Stx) and other virulence factors. Because Stx is coregulated with lambdoid prophage induction, its expression is especially susceptible to environmental cues. Infections with Stx-producing E. coli can be difficult to model due to the wide range of disease outcomes: some infections are relatively mild, while others have serious complications.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

U.S. Department of Agriculture

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.00509-20

Reference153 articles.

1. Pathogenic Escherichia coli

2. Recent Advances in Understanding Enteric Pathogenic Escherichia coli