Activity of Daptomycin against Listeria monocytogenes Isolates from Cerebrospinal Fluid-Reference-Cited by-同舟云学术

Activity of Daptomycin against Listeria monocytogenes Isolates from Cerebrospinal Fluid

Published:2008-05 Issue:5 Volume:52 Page:1850-1851
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Spanjaard Lodewijk¹,Vandenbroucke-Grauls Christina M. J. E.¹

Affiliation:

1. Netherlands Reference Laboratory for Bacterial Meningitis, Department of Medical Microbiology, and Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands

Abstract

ABSTRACT We tested the activity of daptomycin against 76 Listeria monocytogenes isolates from cerebrospinal fluid by broth dilution and Etest methods. For the broth dilution method, the MIC range was 1.0 to 8.0 and the MIC at which 90% of the isolates tested were inhibited (MIC 90 ) was 4.0 mg/liter. For the Etest method, the MIC range was 1.0 to 4.0 and the MIC 90 was 4.0 mg/liter. Presently, daptomycin cannot be recommended for the treatment of L. monocytogenes meningitis.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01139-07

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