Author:
Ameen Sirwan Muhammed,Drancourt Michel
Abstract
ABSTRACTFive type strains and 55Mycobacterium tuberculosiscomplex clinical isolates were found resistant to trimethoprim with a MIC of >200 mg/liter and susceptible to both sulfadiazine and cotrimoxazole with a MIC90of 10 mg/liter. TwoM. canettiiisolates uniquely yielded silent mutations C156→ T and G238→ C in thefolP1gene. Combined with scarce published data, these data indicate that sulfamides could be considered alternative antituberculous antibiotics.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Cited by
22 articles.
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