Biosynthetic Pathway of Citrinin in the Filamentous Fungus Monascus ruber as Revealed by 13 C Nuclear Magnetic Resonance-Reference-Cited by-同舟云学术

Biosynthetic Pathway of Citrinin in the Filamentous Fungus Monascus ruber as Revealed by 13 C Nuclear Magnetic Resonance

Published:1999-01 Issue:1 Volume:65 Page:311-314
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Hajjaj Hassan¹,Klaébé Alain²,Loret Marie O.¹,Goma Gérard¹,Blanc Philippe J.¹,François Jean¹

Affiliation:

1. Centre Bioingénierie Gilbert Durand, CNRS UMR 5504, LA INRA, Institut National des Sciences Appliquées de Toulouse, Complexe Scientifique de Rangueil,1and

2. Laboratoire IMRCP, UMR-CNRS 5623, Groupe de Chimie Organique Biologique, Université Paul Sabatier,2 Toulouse, France

Abstract

ABSTRACT Carbon isotope distribution of [ 13 C]citrinin from Monascus ruber incubated with [ 13 C]acetate revealed that the biosynthesis of the toxin originated from a tetraketide, instead of a pentaketide as has been shown for Penicillium and Aspergillus species. The production of polyketide red pigments and citrinin by M. ruber may therefore be regulated at the level of the tetraketide branch point.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.65.1.311-314.1999

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