Biosynthetic Pathway of Citrinin in the Filamentous Fungus Monascus ruber as Revealed by 13 C Nuclear Magnetic Resonance-Reference-Cited by-同舟云学术

Biosynthetic Pathway of Citrinin in the Filamentous Fungus Monascus ruber as Revealed by 13 C Nuclear Magnetic Resonance

Published:1999-01 Issue:1 Volume:65 Page:311-314
ISSN:0099-2240
Container-title:Applied and Environmental Microbiology
language:en
Short-container-title:Appl Environ Microbiol

Author:

Hajjaj Hassan¹,Klaébé Alain²,Loret Marie O.¹,Goma Gérard¹,Blanc Philippe J.¹,François Jean¹

Affiliation:

1. Centre Bioingénierie Gilbert Durand, CNRS UMR 5504, LA INRA, Institut National des Sciences Appliquées de Toulouse, Complexe Scientifique de Rangueil,1and

2. Laboratoire IMRCP, UMR-CNRS 5623, Groupe de Chimie Organique Biologique, Université Paul Sabatier,2 Toulouse, France

Abstract

ABSTRACT Carbon isotope distribution of [ 13 C]citrinin from Monascus ruber incubated with [ 13 C]acetate revealed that the biosynthesis of the toxin originated from a tetraketide, instead of a pentaketide as has been shown for Penicillium and Aspergillus species. The production of polyketide red pigments and citrinin by M. ruber may therefore be regulated at the level of the tetraketide branch point.

Publisher

American Society for Microbiology

Subject

Ecology,Applied Microbiology and Biotechnology,Food Science,Biotechnology

Link

https://journals.asm.org/doi/pdf/10.1128/AEM.65.1.311-314.1999

Reference16 articles.

1. New insights into polyketide metabolism; the use of protium as a tracer in the biosynthesis of citrinin by Penicillium citrinum.;Barber J.;J. Chem. Soc. Perkin Trans. I,1980

2. Studies in relation to biosynthesis. Part XVII. Sclerotiorin, citrinin, and citromycetin.;Birch A. J.;J. Chem. Soc.,1958

3. Characterization of monascidin A from Monascus as citrinin.;Blanc P. J.;Int. J. Food Microbiol.,1995

4. Biosynthesis of LL-D253a, a polyketide chromanone metabolite of Phoma pigmentivora: incorporation of 13C, 2H and 18O labelled precursors.;Chandler M.;J. Chem. Soc. Perkin Trans. I,1992

5. Biosynthesis of citrinin and synthesis of its biogenetic precursors.;Colombo L.;J. Chem. Soc. Perkin Trans. I,1981

Cited by 118 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mutation Breeding of Monascus to Produce a High Yield of Orange Pigment and Low Citrinin Content Using the ARTP Method;Journal of Fungi;2024-08-05

2. Characterization, components, and chemical structure of a novel natural pigments derived from Streptomyces tauricus;European Food Research and Technology;2024-05-17

3. Selective production, relationship and controversy between Monascus pigments and citrinin;Food Bioscience;2023-12

4. An oxidoreductase gene CtnD involved in citrinin biosynthesis in Monascus purpureus verified by CRISPR/Cas9 gene editing and overexpression;Mycotoxin Research;2023-06-03

5. 药用真菌紫色红曲霉通过CtnC基因调控桔霉素的转运;Journal of Zhejiang University-SCIENCE B;2023-06