Endemic SARS-CoV-2 Polymorphisms Can Cause a Higher Diagnostic Target Failure Rate than Estimated by Aggregate Global Sequencing Data-Reference-Cited by-同舟云学术

Endemic SARS-CoV-2 Polymorphisms Can Cause a Higher Diagnostic Target Failure Rate than Estimated by Aggregate Global Sequencing Data

Published:2021-07-19 Issue:8 Volume:59 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Rhoads Daniel D.¹^ORCID,Plunkett David¹,Nakitandwe Joy¹,Dempsey Andrew¹,Tu Zheng Jin¹,Procop Gary W.¹^ORCID,Bosler David¹,Rubin Brian P.¹,Loeffelholz Michael J.²^ORCID,Brock Jay E.¹

Affiliation:

1. Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio, USA

2. Cepheid, Sunnyvale, California, USA

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.00913-21

Reference7 articles.

1. A Recurrent Mutation at Position 26340 of SARS-CoV-2 Is Associated with Failure of the E Gene Quantitative Reverse Transcription-PCR Utilized in a Commercial Dual-Target Diagnostic Assay

2. Two-step strategy for the identification of SARS-CoV-2 variant of concern 202012/01 and other variants with spike deletion H69–V70, France, August to December 2020

3. S-Gene Target Failure as a Marker of Variant B.1.1.7 Among SARS-CoV-2 Isolates in the Greater Toronto Area, December 2020 to March 2021

4. A Novel Point Mutation in the N Gene of SARS-CoV-2 May Affect the Detection of the Virus by Reverse Transcription-Quantitative PCR

5. SARS-CoV-2 samples may escape detection because of a single point mutation in the N gene

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