Small Noncoding RNA CjNC110 Influences Motility, Autoagglutination, AI-2 Localization, Hydrogen Peroxide Sensitivity, and Chicken Colonization in Campylobacter jejuni

Author:

Kreuder Amanda J.12ORCID,Ruddell Brandon2,Mou Kathy2,Hassall Alan12,Zhang Qijing2,Plummer Paul J.12

Affiliation:

1. Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA

2. Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa, USA

Abstract

Small noncoding RNAs (ncRNAs) are involved in many important physiological functions in pathogenic microorganisms. Previous studies have identified the presence of noncoding RNAs in the major zoonotic pathogen Campylobacter jejuni ; however, few have been functionally characterized to date. CjNC110 is a conserved ncRNA in C. jejuni , located downstream of the luxS gene, which is responsible for the production of the quorum sensing molecule autoinducer-2 (AI-2).

Funder

Iowa State University

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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