Evaluation of Clinical and Economic Efficiency and Impact of Mass Fluorography Screening on Tuberculosis Epidemiological Rates in Four Federal Districts of the Russian Federation with Different Levels of Population Coverage with Mass Fluorography Screening
-
Published:2023-04-27
Issue:2
Volume:101
Page:47-53
-
ISSN:2542-1506
-
Container-title:Tuberculosis and Lung Diseases
-
language:
-
Short-container-title:Tuberk. bolezni lëgk.
Author:
Peretsmanas E. O.1ORCID, Orlova-Morozova E. A.1, Esin I. V.1, Kaminsky G. D.1ORCID, Tyulkova T. E.1ORCID, Panova A. E.1, Lovacheva O. V. O. V.1
Affiliation:
1. National Medical Research Center of Phthisiopulmonology and Infectious Diseases, Russian Ministry of Health, Moscow
Abstract
The objective: analysis of clinical cases of tuberculous spondylitis in HIV-infected patients with the detection of HIV RNA in the focus of vertebral bodies destruction.Subjects and Methods. Medical records of 2 HIV-infected patients who underwent surgery for verified tuberculous spondylitis were analyzed. Parts of the vertebral bodies collected during surgery were examined (PCR, microbiological and histological tests), those were parts with destruction and fragments of healthy iliac bone necessary to fill the implant during corporodesis.Results. RNA HIV was detected in the foci of bone destructionas as well as M. tuberculosis DNA. The viral load in the fragments of healthy iliac bone and peripheral blood of these patients was undetectable.
Publisher
LLC "Medical Knowledge and Technologies"
Reference9 articles.
1. Reshetneva E. V., Mushkin A. Yu., Zimina V. N. Risk analysis for post-surgical complications in tuberculosis spondylitis patients with concurrent HIV infection. Tuberculosis and Lung Diseases, 2015, vol. 4, pp. 36–41. (In Russ.) https://doi.org/10.21292/2075-1230-2015-0-4-36-41 2. Adizie T., Moots R. J., Hodkinson B., French N., Adebajo A. O. Inflammatory arthritis in HIV positive patients: A practical guide. BMC Infect. Dis., 2016, Mar 1, 16:100. doi: 10.1186/s12879-016-1389-2. PMID: 26932524; PMCID: PMC4774153. 3. Ganji R., Dhali S., Rizvi A., Rapole S., Banerjee S. Understanding HIV-Mycobacteria synergism through comparative proteomics of intraphagosomal mycobacteria during mono- and HIV co-infection. Sci. Rep., 2016, Feb 26, 6:22060. doi: 10.1038/srep22060. PMID: 26916387; PMCID: PMC4768096. 4. Lamers S. L., Rose R., Maidji E., Agsalda-Garcia M., Nolan D. J., Fogel G. B., Salemi M., Garcia D. L., Bracci P., Yong W., Commins D., Said J., Khanlou N., Hinkin C. H., Sueiras M. V., Mathisen G., Donovan S., Shiramizu B., Stoddart C. A., McGrath M. S., Singer E. J. HIV DNA is frequently present within pathologic tissues evaluated at Autopsy from Combined Antiretroviral Therapy-Treated Patients with Undetectable Viral Loads. J. Virol., 2016, Sep 29, 90(20), 8968–83. doi: 10.1128/JVI.00674-16. PMID: 27466426; PMCID: PMC5044815. 5. Liebenberg C., Luies L., Williams A. A. Metabolomics as a tool to investigate HIV/TB co-infection. Front Mol. Biosci., 2021, Oct. 20, 8, 692823. doi: 10.3389/fmolb.2021.692823. PMID: 34746228; PMCID: PMC8565463.
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
|
|