Affiliation:
1. Shandong Key Laboratory of Optical Communication Science and Technology, School of Physics Science and Information Technology, Liaocheng University 1 , Liaocheng 252000, China
2. Shandong Liaocheng Laixin Powder Materials Science and Technology Co., Ltd. 2 , Liaocheng 252000, China
Abstract
The ultrafine biosensing technology reveals the mechanisms of various biochemical reactions in cells and the causes of complex diseases through the detection of cellular and subcellular structures. It has an irreplaceable role in the early diagnosis of diseases and in the evaluation of the effectiveness of drug therapy. Due to the complex media composition and ultrafine size of biological cells, traditional sensing technologies can hardly shoulder this difficult task. Nanodiamond (ND) is chemically inert, biocompatible, and nanoscale in size; therefore, it is a safe, non-invasive tool for intracellular sensing. In this Review, we will present the properties of nitrogen vacancy centers, silicon vacancy centers in ND, functionalization of ND, and brief principles of sensing, as well as the latest applications, opportunities, and challenges of ND biosensing.
Funder
Science and Technology Plan of Youth Innovation Team for Universities of Shandong Province
Initial Foundation for Doctor Program of Liaocheng University
Open Project of State Key Laboratory of Superhard Materials
Introduction and Cultivation Plan of Youth Innovation Talents for Universities of Shandong Province
Natural Science Foundation of Shandong Province
Special Construction Project Fund for Shandong Province Taishan Scholars
National Natural Science Foundation of China
Subject
General Engineering,General Materials Science
Cited by
2 articles.
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