Affiliation:
1. Moscow Regional Clinical Research Institute named after M.F. Vladimirsky (MONIKI)
2. I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
3. Skobelkin State Scientific Center of Laser Medicine FMBA
Abstract
This review highlights the possibilities of photodynamic therapy (PDT) using drugs based on chlorin e6, aluminum phthalocyanine, methylene blue as photosensitizers for bacterial and fungal pathologies. This method was developed initially to treat tumor diseases, where it had shown its high efficiency and safety. Now photodynamic therapy is actively used in the treatment of cancers of the skin, bronchi, stomach, cervix, larynx, or other regions. However, numerous studies have been carried out for the entire existence of the method, demonstrating new possibilities of its application. This review highlights a number of studies in which the efficacy and safety of antimicrobial and antimycotic PDT were studied in vivo and in vitro. It has been proven to have a positive effect on the reparative processes in the wound. An experimental study was carried out to study the effectiveness of photodynamic therapy in the treatment of peritonitis in mice. Demonstrated anti-inflammatory potential in the treatment of autoimmune diseases.
Publisher
Russian Photodynamic Association
Reference33 articles.
1. Stranadko E. F., Kuleshov I. Yu., Karakhanov G. Ya. Photodynamic effect on pathogenic microorganisms (current state of the problem of antimicrobial photodynamic therapy). Laser medicine, 2010, No 14 (2), рр. 52–56. (in Russ.)
2. Yang Y., Hu Y., Wang H. Targeting antitumor immune response for enhancing the efficacy of photodynamic therapy of Cancer: recent advances and future perspectives. Oxid Med Cell Longev, 2016, 5274084. doi: 10.1155/2016/5274084
3. Yano T., Wang K.K. Photodynamic therapy for gastrointestinal cancer. Photochem Photobiol, 2020, Vol. 96 (3), pp. 517–523. doi: 10.1111/php.13206.
4. Civantos FJ, Karakullukcu B, Biel M, et al. A Review of Photodynamic Therapy for Neoplasms of the Head and Neck. Advances in Therapy, 2018, Vol. 35, pp. 324–340. doi: 10.1007/s12325–018–0659–3
5. Kwiatkowski S, Knap B, Przystupski D, et al. Photodynamic therapy - mechanisms, photosensitizers and combinations. Biomed Pharmacother, 2018, Vol. 106, pp. 1098–1107. doi: 10.1016/j.biopha.2018.07.049
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