Increased understanding of platinum anticancer chemistry-Reference-Cited by-同舟云学术

Increased understanding of platinum anticancer chemistry

Published:2011-03-31 Issue:9 Volume:83 Page:1709-1719
ISSN:1365-3075
Container-title:Pure and Applied Chemistry
language:
Short-container-title:

Author:

Reedijk Jan¹

Affiliation:

1. 1Department of Chemistry, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia

Abstract

The development of a few worldwide routinely used Pt(II) coordination compounds is described from a mechanistic point of view and related to the molecular aspects of Pt-DNA binding. Mechanistic knowledge developed from these studies is applied nowadays for the design and synthesis of new bifunctional and trifunctional compounds, aimed for use as improved anticancer drugs.

Publisher

Walter de Gruyter GmbH

Subject

General Chemical Engineering,General Chemistry

Link

https://www.degruyter.com/downloadpdf/journals/pac/83/9/article-p1709.xml

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