Nucleic Acid Aptamers Increase the Anticancer Efficiency and Reduce the Toxicity of Cisplatin-Arabinogalactan Conjugates In Vivo

Author:

Zamay Tatiana N.12,Starkov Alexander K.3,Kolovskaya Olga S.12,Zamay Galina S.12,Veprintsev Dmitry V.1,Luzan Natalia2,Nikolaeva Elena D.12,Lukyanenko Kirill A.124,Artyushenko Polina V.124,Shchugoreva Irina A.124,Glazyrin Yury E.12,Koshmanova Anastasia A.12,Krat Alexey V.2,Tereshina Dariya S.2,Zamay Sergey S.1,Pats Yuriy S.2,Zukov Ruslan A.2,Tomilin Felix N.45,Berezovski Maxim V.6,Kichkailo Anna S.12ORCID

Affiliation:

1. Laboratory for Digital Controlled Drugs and Theranostics, Federal Research Center “Krasnoyarsk Research Center” of the Siberian Branch of the Russian Academy of Science, Krasnoyarsk, Russia.

2. Laboratory For Biomolecular and Medical Technologies, Krasnoyarsk State Medical University named after Prof. V.F. Voino-Yasenecky, Krasnoyarsk, Russia.

3. Institute of Chemistry and Chemical Technology SB RAS, Federal Research Center “Krasnoyarsk Science Center SB RAS,” Krasnoyarsk, 660036, Russia.

4. Department of Chemistry, Siberian Federal University, Krasnoyarsk, Russia.

5. Laboratory for Physics of Magnetic Phenomena, Kirensky Institute of Physics, Federal Research Center Krasnoyarsk Science Center SB RAS, Krasnoyarsk, Russia.

6. Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Ontario, Canada.

Publisher

Mary Ann Liebert Inc

Subject

Drug Discovery,Genetics,Molecular Biology,Molecular Medicine,Biochemistry

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