Synthesis, Characterization and in Vitro Antimicrobial Studies of Ternary Mn(II) Complexes with Isatinphenylhydrazone, Glycine and 8-hydroxyquinoline

Abstract

In our present research work, we have synthesized two ternary metal complexes of Mn(II), complex-I as [Mn(L)(Gly)(Cl)(H2O)] and complex-II as [Mn(L)(Q)(Cl)(H2O)]; where L is Isatinphenylhydrazone (IPH) as primary ligand, whereas glycine (Gly) and 8-hydroxyquinoline (HQ) as secondary ligand in complex-I and II respectively, in 1:1:1 (M : L : Gly or M : L : Q) molar ratios. Above synthesized complexes are employed for characterization using various analytical techniques including elemental analysis, melting point determination, magnetic moment measurements, molar conductance measurements, and spectral techniques (FTIR, UV, 1H NMR) etc. Further, their antimicrobial activities were evaluated against selected bacterial strains i.e., B. subtilis, S. aureus (Gram positive) and P. aeruginosa, E. coli (Gram negative) and fungal strains (T. reesei, A. niger, C. albicans) and found significantly active.