HPLC Analysis of Chemical Composition of Selected Jordanian Medicinal Plants and Their Bioactive Properties-Reference-Cited by-同舟云学术

HPLC Analysis of Chemical Composition of Selected Jordanian Medicinal Plants and Their Bioactive Properties

Published:2018-10-17 Issue:5 Volume:34 Page:2397-2403
ISSN:0970-020X
Container-title:Oriental Journal of Chemistry
language:
Short-container-title:Orient. J. Chem

Author:

Al-Rimawi Fuad¹^ORCID,Alakhras Fadi²^ORCID,Al-Zereini Wael A.³^ORCID,Aldal'in Hammad K.⁴^ORCID,Abu-Lafi Saleh⁵,Al-Mazaideh Ghassab M.⁶^ORCID,Ayyal Salman Haya J.³^ORCID

Affiliation:

1. Department of Chemistry, Faculty of Science and Technology, Al-Quds University, P.O. Box 20002, Jerusalem, Palestine.

2. Department of Chemistry, College of Science, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.

3. Department of Biological Sciences, Faculty of Science, Mutah University, P.O. Box 7, Mutah 61710, Al-Karak, Jordan.

4. Department of Medical Support, Al-Balqa Applied University, Al-Karak University College, Al-Karak, Jordan.

5. Faculty of Pharmacy, Al-Quds University, P.O. Box 20002, Jerusalem, Palestine.

6. Department of Chemistry and Chemical Technology, Faculty of Science, Tafila Technical University, P.O. Box 179, Tafila 66110, Jordan.

Abstract

Three medicinal plants grown wild in Jordan, namely Achillea santolina L, Achillea fragrantisimma, Asteriscus graveolens (Forssk) Less, were extracted with ethyl acetate by continuous shaking at room temperature for three days. The antibacterial activity of the crude extract was evaluated. The extracts were analyzed for their phenolic and flavonoids content by HPLC-PDA. The HPLC analysis of the plant extracts revealed the presence of flavonoids and phenolic compounds in the three plant extracts. Results revealed a strong antibacterial activity of A. graveolens against three bacterial strains (B. subtilis, E. coli, and S.aureus) while A. fragrantissima inhibited the growth of B. subtilis. Bioactivities were attributed mainly to the immense content of phenol-based compounds in plants.

Publisher

Oriental Scientific Publishing Company

Subject

Drug Discovery,Environmental Chemistry,Biochemistry,General Chemistry

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