Comparison of Efficacy of Diclofenac and Paracetamol as Preemptive Analgesic Agent

Author:

Thenarasu Vinishdharma1,Gurunathan Deepa2,Santhosh Kumar M.P.3

Affiliation:

1. Saveetha Dental College, Saveetha Institute of Medical and Technical Science (SIMATS) Saveetha University, Chennai, India.

2. Department of Pedodontics Saveetha Dental College, Saveetha Institute of Medical and Technical Science (SIMATS) Saveetha University, Chennai, India.

3. Department of Oral and Maxillofacial Surgery Saveetha Dental College, Saveetha Institute of Medical and Technical Science(SIMATS) Saveetha University, Chennai, India.

Abstract

Extraction of teeth has been a common, routine dental procedure done in clinics which may lead to moderate to severe pain postoperatively. Any pain postoperatively may cause a discomfort in particpants and affects their routine lifestyle. Preemptive analgesics plays an important role in reducing postoperative pain and distress associated with painful dental procedures. Nonsteroidal anti-inflammatory drugs are one of the treatment options to be used as pain relief for surgical teeth extraction. Wherelse, another commonly prescribed drug over-the-counter is Paracetamol. The purpose of this study is to evaluate the analgesic effect of both the drug as an preemptive analgesia. This study is a double blind , clinical trial. Twenty particpants were randomised into two group. Group A receiving Paracetamol (500mg) and Group B receiving Diclofenac (100mg) orally, 30 minute before the extraction is done. The pain intensity and the duration of the analgesia is evaluated using the Visual Analog Scale (VAS). Patient who were given Diclofenac (100mg) show a higher analgesic effect compare to Paracetamol (500mg).However, the analgesic effect in patient received Diclofenac is much more longer then patient received Paracetemol. Two different drug has been used in this study to evaluate their efficacy as an preemptive analgesic and it can be concluded that Diclofenac is more effective then Paracetamol as an preemptive analgesia.

Publisher

Oriental Scientific Publishing Company

Subject

Pharmacology

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