Absorption of iron from ferric hydroxypyranone complexes

Author:

Maxton D. G.,Thompson R. P. H.,Hider R. C.

Abstract

The absorption of 59Fe from preparations of FeSO4 and the ferric hydroxypyranone complexes maltol and ethyl maltol was studied by whole-body counting in normal subjects and patients with Fe deficiency. Fe in the Fe3+ complexes was in general absorbed almost as well as Fe2+. It is concluded that the absorption of Fe3+ from hydroxypyranone complexes is much greater than that from simple Fe3+ salts; this may prove an efficient and less toxic form of Fe for the treatment of deficiency.

Publisher

Cambridge University Press (CUP)

Subject

Nutrition and Dietetics,Medicine (miscellaneous)

Reference18 articles.

1. Hydroxyl radicals and the toxicity of oral iron

2. The fate of iron compounds in the gastrointestinal tract;Schneider;Arzneimittel Forschnung,1987

3. Iron complexes of maltol;Gerard;Journal of Chemica1 Research,1980

4. Metabolism of ethyl maltol and maltol in the dog

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