Nghiên cứu mối liên quan giữa nồng độ ima (Ischemia modified albumin) và mức độ tổn thương động mạch vành ở bệnh nhân hội chứng vành cấp

Abstract

RESEARCH THE CORRELATION BETWEEN IMA CONCENTRATION AND DEGREE OF CORONARY ARTERY LESIONS IN PATIENTS WITH ACUTE CORONARY SYNDROME Introduction: Coronary artery lesions were the main cause of ACS, the character of coronary artery lesion and how is IMA concentrations correlated with degree of coronary artery lesion in acute coronary syndrome? Objective: Survey character of coronary artery lesions in patients with acute coronary syndrome through the results of angiography and correlation between the concentration of IMA and degree of coronary artery lesions in patients with acute coronary syndrome. Subject and Method: 130 patients at the Cardiology Center-Hue Central Hospital are diagnosed acute coronary syndrome according to the Fourth universal definition of myocardial infarction 2018. In which 103 patients were taken angiography and evaluated the coronary artery lesions follow GENSINI scale. Result: Research conducted on 130 patients, including 85 males and 45 females with the proportion of male: female is 1.89, average age: 65.7 ± 12.3years old. There are 91.3% of patients with coronary artery lesions higher than coronary artery non lesions (p <0.001). Injury of one branch accounted for 35,9%, two branch accounted for 34.0% and three branch injuries accounted for 21.4%.. There are 79.6% in LAD injury and 58.3% in RCA, accounting for 41.7% in LCx. The lesions stenosis that more than 75% is accounted for the highest percentage 70.59%. GENSINI score average is 27.80 ± 25.92 and median score is 21 points. There is no correlation between the concentration of IMA and the branching coronary lesions with r = - 0,046, p > 0.05. There is no correlation between the concentration of IMA and GENSINI scores with r = - 0,064, p> 0,05. Conclusions: LAD lesions accounted for the highest percentage, lesions more than one coronary artery branch also high percentage and severe coronary stenosis is highest proportion in acute coronary syndrome. There is no correlation between the IMA concentration and the number of branching coronary lesions, as well as GENSINI scores. Key words: IMA, Coronay artery lesions, ACS.