Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach-Reference-Cited by-同舟云学术

Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach

Published:2016-01 Issue:1 Volume:22 Page:361-379
ISSN:1076-1551
Container-title:Molecular Medicine
language:en
Short-container-title:Mol Med

Author:

Chao Celia,Zatarain John R,Ding Ye,Coletta Ciro,Mrazek Amy A,Druzhyna Nadiya,Johnson Paul,Chen Haiying,Hellmich Judy L,Asimakopoulou Antonia,Yanagi Kazunori,Olah Gabor,Szoleczky Petra,Törö Gabor,Bohanon Fredrick J,Cheema Minal,Lewis Rachel,Eckelbarger David,Ahmad Akbar,Módis Katalin,Untereiner Ashley,Szczesny Bartosz,Papapetropoulos Andreas,Zhou Jia,Hellmich Mark R,Szabo Csaba

Publisher

Springer Science and Business Media LLC

Subject

Genetics(clinical),Genetics,Molecular Biology,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.2119/molmed.2016.00102.pdf

Reference46 articles.

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2. Szabo C, et al. (2013) Tumor-derived H2S, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation and angiogenesis in colon cancer. Proc. Natl. Acad. Sci. U. S. A. 110:12474–79.

3. Módis K, et al. (2014) Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro. Nitric Oxide. 41:146–56.

4. Hellmich MR, Coletta C, Chao C, Szabo C. (2015) The therapeutic potential of cystathionine-β-synthase inhibition in cancer. Antioxid. Redox Signal. 22:424–48.

5. Szabo C. (2016) Gasotransmitters in cancer: From pathophysiology to experimental therapy. Nat. Rev. Drug. Discov. 15:185–203.

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