Review of Hydrogen Sulfide Based on Its Activity Mechanism and Fluorescence Sensing

Author:

Zhang Jinlong1,Jing Quan12,Gao Fei12,Zhang Fuxin12,Pei Dong1,Di Duolong1,Hai Jun1ORCID

Affiliation:

1. CAS Key Laboratory of Chemistry of Northwestern Plant Resources and Key Laboratory of Natural Medicine of Gansu Province, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730099, China

2. University of Chinese Academy of Sciences, Beijing 100049, China

Abstract

The significance of hydrogen sulfide (H2S) in biological research is covered in detail in this work. H2S is a crucial gas-signaling molecule that is involved in a wide range of illnesses and biological processes. Whether H2S has a beneficial therapeutic effect or negative pathological toxicity in an organism depends on changes in its concentration. A novel approach to treatment is the regulation of H2S production by medications or other measures. Furthermore, H2S is a useful marker for disease assessment because of its dual nature and sensitivity. We can better understand the onset and progression of disease by developing probes to track changes in H2S concentration based on the nucleophilicity, reducing properties, and metal coordination properties of H2S. This will aid in diagnosis and treatment. These results demonstrate the enormous potential of H2S in the detection and management of disease. Future studies should concentrate on clarifying the relationship between diseases and the mechanism of action of H2S in organisms. Ultimately, this work opens new possibilities for disease diagnosis and treatment while highlighting the significance of H2S in biological research. Future clinical practice and medical advancements will benefit greatly from our thorough understanding of the mechanism of action and therapeutic applications of H2S.

Funder

Key R&D Program of Yunnan Province

Yunnan Province Major Scientific and Technological Project

Young Researcher Program of the Lanzhou Institute of Chemical Physics

Publisher

MDPI AG

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