Dual Targeting of mTOR Activity with Torin2 Potentiates Anticancer Effects of Cisplatin in Epithelial Ovarian Cancer-Reference-Cited by-同舟云学术

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Dual Targeting of mTOR Activity with Torin2 Potentiates Anticancer Effects of Cisplatin in Epithelial Ovarian Cancer

Published:2015-01 Issue:1 Volume:21 Page:466-478
ISSN:1076-1551
Container-title:Molecular Medicine
language:en
Short-container-title:Mol Med

Author:

Hussain Azhar R.,Al-Romaizan Maha,Ahmed Maqbool,Thangavel Saravanan,Al-Dayel Fouad,Beg Shaham,Uddin Shahab,Siraj Abdul K.,Al-Kuraya Khawla S.

Publisher

Springer Science and Business Media LLC

Subject

Genetics (clinical),Genetics,Molecular Biology,Molecular Medicine

Link

http://link.springer.com/content/pdf/10.2119/molmed.2014.00238.pdf

Reference50 articles.

1. Noske A. (2014) [Heterogeneity of epithelial ovarian carcinomas and their clinical significance]. Praxis. (Bern 1994). 103:155–9.

2. Meinhold-Heerlein I, Hauptmann S. (2014) The heterogeneity of ovarian cancer. Arch. Gynecol. Obstet. 289:237–9.

3. Colombo PE, et al. (2014) Sensitivity and resistance to treatment in the primary management of epithelial ovarian cancer. Crit. Rev. Oncol. Hematol. 89:207–16.

4. Coleman RL, Monk BJ, Sood AK, Herzog TJ. (2013) Latest research and treatment of advanced-stage epithelial ovarian cancer. Nat. Rev. Clin. Oncol. 10:211–24.

5. Marcus CS, Maxwell GL, Darcy KM, Hamilton CA, McGuire WP. (2014) Current approaches and challenges in managing and monitoring treatment response in ovarian cancer. J Cancer5:25–30.

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1. Anti-inflammatory effects of Torin2 on lipopolysaccharide-treated RAW264.7 murine macrophages and potential mechanisms;Heliyon;2022-07

2. Torin2 overcomes sorafenib resistance via suppressing mTORC2-AKT-BAD pathway in hepatocellular carcinoma cells;Hepatobiliary & Pancreatic Diseases International;2020-12

3. Research progress of mTOR inhibitors;European Journal of Medicinal Chemistry;2020-12

4. Torin2 inhibits the EGFR-TKI resistant Non-Small Lung Cancer cell proliferation through negative feedback regulation of Akt/mTOR signaling;Journal of Cancer;2020

5. Cisplatin based therapy: the role of the mitogen activated protein kinase signaling pathway;Journal of Translational Medicine;2018-04-11

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