Update on the Current Landscape of Transcatheter Options for Tricuspid Regurgitation Treatment

Author:

Curio Jonathan1,Demir Ozan M2,Pagnesi Matteo3,Mangieri Antonio4,Giannini Francesco4,Weisz Giora5,Latib Azeem5

Affiliation:

1. Unit of Cardiovascular Interventions, IRCCS San Raffaele Scientific Institute, Milan, Italy; Charité University Medical Care, Berlin, Germany

2. Department of Cardiology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, UK

3. Unit of Cardiovascular Interventions, IRCCS San Raffaele Scientific Institute, Milan, Italy

4. Interventional Cardiology Unit, GVM Care & Research Maria Cecilia Hospital, Cotignola, Italy

5. Department of Cardiology, Montefiore Medical Center, New York, NY, US

Abstract

Most patients with severe tricuspid regurgitation lack treatment options because of prohibitive surgical risk. New transcatheter treatments under development and investigation might be able to address this unmet clinical need. This article gives an update on the landscape of devices for transcatheter tricuspid regurgitation treatment including different approaches (i.e. repair with leaflet approximation or annuloplasty and replacement using orthotopic or heterotopic valves) at different stages of development, from experimental to clinical trial. Repair devices such as the Cardioband or the MitraClip are leading the field with promising preliminary data and further trials are ongoing. However, with implantations of the Gate bioprosthesis, replacement devices are catching up. Potential advantages of different approaches and most recent data are discussed.

Publisher

Radcliffe Group Ltd

Subject

Cardiology and Cardiovascular Medicine

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