Affiliation:
1. Pirogov Russian National Research Medical University
Abstract
The main clinical manifestation of osteoporosis is a low-energy fracture. Fracture is associated with a high risk of disability and mortality. Therefore, the aim of osteoporosis treatment is to reduce the risk of fractures. Therefore, experts from the UK in 2019 developed and put into practice a fracture risk stratification system, on the basis of which a decision is made on the treatment of patients with osteoporosis. So patients with a very high risk of fractures need to prescribe anabolic therapy, followed by the appointment of antiresorptive drugs. Patients at high risk – the appointment of antiresorptive therapy, and if it is ineffective, the appointment of anabolic therapy. Patients with low and intermediate risk are recommended dynamic monitoring with constant reassessment of the risk of fractures. This conclusion completely changes the existing paradigm of osteoporosis treatment.
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