First results of the register of patients with osteoporosis included in the secondary fracture prevention services

Author:

Belova K. Yu.1ORCID,Bublik E. V.2ORCID,Gladkova E. N.3ORCID,Gordjeladze H. G.4,Dudinskaya E. N.5ORCID,Ladygina D. O.2ORCID,Morozova M. S.4,Polyakova Yu. V.6ORCID,Sivordova L. E.6ORCID,Tanaev V. G.7ORCID,Lesnyak O. M.3ORCID

Affiliation:

1. Yaroslavl State Medical University; Solovyov A&E Clinical Hospital

2. Central clinical hospital with outpatient health center of the Business Administration for the President of the Russian Federation

3. North-Western state medical University named after I.I. Mechnikov; Clinical rheumatology hospital № 25

4. Solovyov A&E Clinical Hospital

5. Pirogov National Research Medical University, Russian Gerontology Research and Clinical Centre

6. Zborovsky Research Institute of Clinical and Experimental Rheumatology

7. Clinical rheumatology hospital № 25

Abstract

Background. To reduce the number of osteoporotic fractures in the world in recent years, — Fracture Liaison Service has been created. Since 2019, the development of a register of patients included in the Secondary Fracture Prevention named «Prometheus» has begun in Russia.Materials and methods. An information system for storing, searching and processing information has been created, and a registration card has been developed. Six FLS participate in the register management. As of 10.03.2021, data on 387 patients were introduced in the register.Results. Among the included patients, 46.25% received a fracture of the proximal femur, 20.41% — of the vertebral bodies and 16.80% of the proximal humerus, the rest had fractures of other localizations. The risk of fractures was assessed in all patients. A high risk of major osteoporotic fractures according to FRAX was determined in 160 (43.24%) people. Two-energy X-ray absorptiometry (DXA) was performed in 152 (39.28%) patients, and osteoporosis was detected in 103 (67.76%), osteopenia — in 42 (27.63%) patients. The risk of falls was assessed in 100% of the included patients, and the risk of falls was determined to be high in 343 (88.63%) patients. Evaluation of various laboratory parameters to find the causes of secondary osteoporosis was performed in most patients. After consultation with the FLS doctor, anti-osteoporotic drugs were prescribed to 241 (64.27%) people. Among the rest, 70 (52.24%) patients had contra-indications and 31 (23.13%) people needed further examination.Conclusions. Thus, the use of the register allows you to evaluate all the main sections of the organization of assistance within the FLS and compare them with international standards to identify «gaps» and improve the work of the service.

Publisher

Autonomous non-profit organization-Society of Specialists in the Field Innovative Medical Technology

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