Biomechanical properties, pathogenetic mechanisms and pathways of infection of tissue-engineered vascular conduits in angiosurgery

Abstract

We have reviewed scientific publications dealing with the problem of the use of tissue-engineered materials in vascular surgery. The review presents the pros and cons of applicable conduits, describes in detail the biomechanical properties of tissue-engineered vascular conduits. However, the functioning of conduits depends on their ability to mimic the mechanical and biological behave our of the artery. The article describes the transmission of infection to vascular conduits, as well as presents the pathogenetic mechanisms, possible pathways of infections and their concomitance with the description of possible infectious agents, analyzes the ways and methods to improve the functional characteristics of existing tissue-engineered vascular conduits.