Spinal cord motor neuron phenotypes and polygenic risk scores in sporadic amyotrophic lateral sclerosis: deciphering the disease pathology and therapeutic potential of ropinirole hydrochloride-Reference-Cited by-同舟云学术

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Spinal cord motor neuron phenotypes and polygenic risk scores in sporadic amyotrophic lateral sclerosis: deciphering the disease pathology and therapeutic potential of ropinirole hydrochloride

Published:2024-09-04 Issue: Volume: Page:jnnp-2024-333690
ISSN:0022-3050
Container-title:Journal of Neurology, Neurosurgery & Psychiatry
language:en
Short-container-title:J Neurol Neurosurg Psychiatry

Author:

Kato Chris,Morimoto Satoru^ORCID,Takahashi Shinichi^ORCID,Namba Shinichi^ORCID,Wang Qingbo S^ORCID,Okada Yukinori^ORCID,Okano Hideyuki^ORCID

Funder

Japan Agency for Medical Research and Development

UBE Academic Foundation

Yoshio Koide Grant, Japan ALS Association

Daiichi Sankyo Foundation of Life Science

Japan Society for the Promotion of Science

Miyata Yukihiko Memorial ALS Research Grant Foundation

Publisher

BMJ

Reference5 articles.

1. Modeling sporadic ALS in iPSC-derived motor neurons identifies a potential therapeutic agent;Fujimori;Nat Med,2018

2. Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery

3. Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology

4. Neutral Lipid Cacostasis Contributes to Disease Pathogenesis in Amyotrophic Lateral Sclerosis

5. Defective cholesterol metabolism in amyotrophic lateral sclerosis

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