Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery-Reference-Cited by-同舟云学术

Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery

Published:2023-06 Issue:6 Volume:30 Page:766-780.e9
ISSN:1934-5909
Container-title:Cell Stem Cell
language:en
Short-container-title:Cell Stem Cell

Author:

Morimoto Satoru,Takahashi Shinichi,Ito Daisuke,Daté Yugaku,Okada Kensuke,Kato Chris,Nakamura Shiho,Ozawa Fumiko,Chyi Chai Muh,Nishiyama Ayumi,Suzuki Naoki,Fujimori Koki,Kondo Tosho,Takao Masaki,Hirai Miwa,Kabe Yasuaki,Suematsu Makoto,Jinzaki Masahiro,Aoki Masashi,Fujiki Yuto,Sato Yasunori,Suzuki Norihiro,Nakahara Jin,Okano Hideyuki

Publisher

Elsevier BV

Subject

Cell Biology,Genetics,Molecular Medicine

Reference91 articles.

1. Riluzole and edaravone: a tale of two amyotrophic lateral sclerosis drugs;Jaiswal;Med. Res. Rev.,2019

2. An evaluation of the combination of sodium phenylbutyrate and taurursodiol for the treatment of amyotrophic lateral sclerosis;Sun;Expert Rev. Neurother.,2023

3. Trends in clinical success rates and therapeutic focus;Dowden;Nat. Rev. Drug Discov.,2019

4. iPSC-based disease modeling and drug discovery in cardinal neurodegenerative disorders;Okano;Cell Stem Cell,2022

5. Ropinirole, a new ALS drug candidate developed using iPSCs;Okano;Trends Pharmacol. Sci.,2020

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of 5-phenyl-3-ureidothiophene-2-carboxamides as protective agents for ALS patient iPSC-derived motor neurons;Bioorganic & Medicinal Chemistry Letters;2024-11

2. Modelling neurocardiac physiology and diseases using human pluripotent stem cells: current progress and future prospects;The Journal of Physiology;2024-09-05

3. Spinal cord motor neuron phenotypes and polygenic risk scores in sporadic amyotrophic lateral sclerosis: deciphering the disease pathology and therapeutic potential of ropinirole hydrochloride;Journal of Neurology, Neurosurgery & Psychiatry;2024-09-04

4. The 2023 yearbook of Neurorestoratology;Journal of Neurorestoratology;2024-09

5. Establishment of a novel amyotrophic lateral sclerosis patient (TARDBPN345K/+)-derived brain microvascular endothelial cell model reveals defective Wnt/β-catenin signaling: investigating diffusion barrier dysfunction and immune cell interaction;Frontiers in Cell and Developmental Biology;2024-08-15