The Role of High-Density Lipoprotein in Cardiovascular Disease: Benefits, Functions, and Treatments

Author:

Xiong Yali

Abstract

There is evidence that high-density lipoprotein (HDL) can prevent the development of cardiovascular disease, particularly atherosclerotic. The beneficial effects of HDL on the arterial wall are largely due to its rich function. For example, one of the essential components of HDL's atherosclerotic protective characteristics is reverse cholesterol transport (RCT). The low-density lipoprotein (LDL) oxidation risk may be decreased attributable to the anti-oxidation function of HDL, which would also decrease the possibility of atherosclerosis. In recent years, the anti-inflammatory function of HDL has been demonstrated to modulate and participate in several inflammatory phenomena of atherosclerotic plaque formation. Since various functional features of HDL have gradually shown to have positive effects on the treatment and prevention of atherosclerotic plaque development, a growing number of researchers are working to develop effective strategies to boost HDL. Fortunately, several treatment options have developed to increase HDL levels, including drugs and dietary patterns. This article will focus on the functional properties of HDL levels and several therapeutic approaches to raise HDL levels.

Publisher

Darcy & Roy Press Co. Ltd.

Reference11 articles.

1. Ellie Whitney Sharon Rady Rolfes, Gail Hammond, Leonard A. Piché. Chapter: 19 Diet and Health. Understanding nutrition, Second Canadian Edition Cengage Learning, 2015, pp. 636–637.

2. Kjeldsen Emilie Westerlin, Thomassen Jesper Qvist,Frikke-Schmidt Ruth. HDL cholesterol concentrations and risk of atherosclerotic cardiovascular disease – Insights from randomized clinical trials and human genetics. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2022, 1867(1): 159063.

3. Ellie Whitney Sharon Rady Rolfes, Gail Hammond, Leonard A. Piché. Chapter 5: The Lipids: Triglycerides, Phospholipids, and Sterols. Understanding nutrition, Second Canadian Edition. Cengage Learning, 2015, pp. 153–154.

4. Ellie Whitney Sharon Rady Rolfes, Gail Hammond, Leonard A. Piché. Chapter 19: Diet and Health. Understanding nutrition, Second Canadian Edition Cengage Learning, 2015, p. 639.

5. Ellie Whitney Sharon Rady Rolfes, Gail Hammond, Leonard A. Piché. Chapter 5: The Lipids: Triglycerides, Phospholipids, and Sterols. Understanding nutrition, Second Canadian Edition. Cengage Learning, 2015, p. 148.

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3