Cancer Research Using Crispr/Cas9 Gene Editing Technology

Abstract

Gene editing technology has completely transformed the life sciences and medical treatment, because it makes precise and stable genetic alterations to genomic sequences possible. Among gene editing technologies, CRISPR system is now the most employed one. CRISPR technology is currently often used in the medical field including cancer study as well as genome editing in a number of animals. Besides, the CRISPR system has been widely used in agriculture, industry and other fields, such as crop breeding, industrial microbial design, viral nucleic acid detection, etc. In the framework of people’s knowledge of cancer research and genome editing technology, this paper focuses on the adhibition of CRISPR/Cas9 in cancer modeling, high throughput genetic analysis of tumor cell metastasis-related genes, as well as cancer treatment. It indicates that CRISPR/Cas9 techniques can be a promising tool in cancer diagnostics and therapeutics. Although CRISPR / Cas9 technology has limitations such as being off-target, this technology undoubtedly has great potential in cancer or other diseases in the future.