Binding of longer Aβ to transmembrane domain 1 of presenilin 1 impacts on Aβ42 generation-Reference-Cited by-同舟云学术

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Binding of longer Aβ to transmembrane domain 1 of presenilin 1 impacts on Aβ42 generation

Published:2014-01-13 Issue:1 Volume:9 Page:
ISSN:1750-1326
Container-title:Molecular Neurodegeneration
language:en
Short-container-title:Mol Neurodegeneration

Author:

Ohki Yu,Shimada Naoaki,Tominaga Aya,Osawa Satoko,Higo Takuya,Yokoshima Satoshi,Fukuyama Tohru,Tomita Taisuke,Iwatsubo Takeshi

Publisher

Springer Science and Business Media LLC

Subject

Cellular and Molecular Neuroscience,Clinical Neurology,Molecular Biology

Link

https://link.springer.com/content/pdf/10.1186/1750-1326-9-7.pdf

Reference47 articles.

1. Holtzman DM, Morris JC, Goate AM: Alzheimer's disease: the challenge of the second century. Sci Transl Med. 2011, 3: 77sr71-

2. Iwatsubo T, Odaka A, Suzuki N, Mizusawa H, Nukina N, Ihara Y: Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43). Neuron. 1994, 13: 45-53.

3. De Strooper B, Annaert W: Novel research horizons for presenilins and gamma-secretases in cell biology and disease. Annu Rev Cell Dev Biol. 2010, 26: 235-260.

4. Takasugi N, Tomita T, Hayashi I, Tsuruoka M, Niimura M, Takahashi Y, Thinakaran G, Iwatsubo T: The role of presenilin cofactors in the gamma-secretase complex. Nature. 2003, 422: 438-441.

5. Tomita T, Iwatsubo T: Structural biology of presenilins and signal peptide peptidases. J Biol Chem. 2013, 288: 14673-14680.

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2. Structure of γ-secretase (PSEN1/APH-1B) in complex with Aβ46 provides insights into amyloid-β processing and modulation by the APH-1B isoform;2023-09-09

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4. Calmodulin and Amyloid Beta as Coregulators of Critical Events during the Onset and Progression of Alzheimer’s Disease;International Journal of Molecular Sciences;2023-01-11

5. Presenilin/γ-Secretase in the Pathogenesis of Alzheimer’s Disease;Aging Mechanisms II;2022

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