Identification of potential synthetic lethal genes to p53 using a computational biology approach
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics (clinical),Genetics
Link
http://link.springer.com/content/pdf/10.1186/1755-8794-6-30.pdf
Reference83 articles.
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3. Canaani D: Methodological approaches in application of synthetic lethality screening towards anticancer therapy. Br J Cancer. 2009, 100 (8): 1213-1218. 10.1038/sj.bjc.6605000.
4. Mizuarai S, et al: Integrated genomic and pharmacological approaches to identify synthetic lethal genes as cancer therapeutic targets. Curr Mol Med. 2008, 8 (8): 774-783. 10.2174/156652408786733676.
5. Mizuarai S, Yamanaka K, Kotani H: Mutant p53 induces the GEF-H1 oncogene, a guanine nucleotide exchange factor-H1 for RhoA, resulting in accelerated cell proliferation in tumor cells. Cancer Res. 2006, 66 (12): 6319-6326. 10.1158/0008-5472.CAN-05-4629.
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