Author:
Chang Saishuo,Lin Yu,Yang Shen,Yang Wei,Cheng Haiyan,Chang Xiaofeng,Zhu Zhiyun,Feng Jun,Han Jianyu,Ren Qinghua,Wang Huanmin,Qin Hong
Abstract
Abstract
Objective
To explore the criteria, safety and efficacy of laparoscopic surgery in pediatric neuroblastoma (NB).
Methods
A retrospective study of 87 patients with NB without image-defined risk factors (IDRFs) between December 2016 and January 2021 at Beijing Children’s Hospital was conducted. Patients were divided into two groups according to the surgical procedure.
Results
Between the 87 patients, there were 54 (62.07%) cases in the open surgery group and 33 (37.93%) cases in the laparoscopic surgery group. There were no significant differences between the two groups regarding demographic characteristics, genomic and biological features, operating time or postoperative complications. However, in terms of intraoperative bleeding (p = 0.013) and the time to start postoperative feeding after surgery (p = 0.002), the laparoscopic group was obviously better than the open group. Furthermore, there was no significant difference in the prognosis between the two groups, and no recurrence or death was observed.
Conclusion
For children with localized NB who have no IDRFs, laparoscopic surgery could be performed safely and effectively. Surgeons who are skilled in this can help children reduce surgical injuries, speed up postoperative recovery, and obtain the same prognosis as open surgery.
Publisher
Springer Science and Business Media LLC
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