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Neuroblastoma

Published:2016-11-10 Issue:1 Volume:2 Page:
ISSN:2056-676X
Container-title:Nature Reviews Disease Primers
language:en
Short-container-title:Nat Rev Dis Primers

Author:

Matthay Katherine K.,Maris John M.,Schleiermacher Gudrun,Nakagawara Akira,Mackall Crystal L.,Diller Lisa,Weiss William A.

Publisher

Springer Science and Business Media LLC

Subject

General Medicine

Link

http://www.nature.com/articles/nrdp201678.pdf

Reference215 articles.

1. Stiller, C. A. & Parkin, D. M. International variations in the incidence of neuroblastoma. J. Int. Cancer 52, 538–543 (1992).

2. London, W. B. et al. Evidence for an age cutoff greater than 365 days for neuroblastoma risk group stratification in the Children's Oncology Group. J. Clin. Oncol. 23, 6459–6465 (2005).

3. Thompson, D. et al. Identification of patient subgroups with markedly disparate rates of MYCN amplification in neuroblastoma: a report from the International Neuroblastoma Risk Group project. Cancer 122, 935–945 (2016).

4. Schleiermacher, G. et al. Accumulation of segmental alterations determines progression in neuroblastoma. J. Clin. Oncol. 28, 3122–3130 (2010). Comparison at diagnosis and relapse of DNA ploidy and array comparative genomic hybridization for segmental chromosomal aberrations in 394 patients with neuroblastoma showed that further changes evolve at recurrence, even in patients treated with surgery alone, suggesting that patients should be re-evaluated at relapse.

5. Pugh, T. J. et al. The genetic landscape of high-risk neuroblastoma. Nat. Genet. 45, 279–284 (2013). This comprehensive study using exome, genome and transcriptome analysis identified some important germline and somatic mutations in 240 neuroblastomas, as well as the relatively low frequency of somatic mutations at diagnosis.

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