Author:
Ra Song-Gyu,Miyazaki Teruo,Ishikura Keisuke,Nagayama Hisashi,Komine Shoichi,Nakata Yoshio,Maeda Seiji,Matsuzaki Yasushi,Ohmori Hajime
Abstract
Abstract
Background
Previous studies have evaluated the effectiveness of branched-chain amino acid (BCAA) supplementation for preventing delayed onset muscle soreness (DOMS) and muscle damage induced by eccentric exercise, their findings have been inconclusive. Since taurine has anti-inflammatory and anti-oxidative effects, the present study investigated the combined effect of BCAA and taurine on DOMS and muscle damage.
Methods
Thirty-six untrained male subjects (22.5 ± 3.8 years) were assigned to four groups (placebo + placebo [placebo], BCAA + placebo, placebo + taurine, and BCAA + taurine [combined]) and given a combination of 3.2 g BCAA (or placebo) and 2.0 g taurine (or placebo), three times a day, for two weeks prior to and three days after eccentric elbow flexor exercises. DOMS and muscle damage in the biceps brachii were subjectively and objectively evaluated using the visual analogue scale (VAS), upper arm circumference (CIR), and blood parameters (creatine kinase, lactate dehydrogenase [LDH], aldolase, and 8-hydroxydeoxyguanosine [8-OHdG]).
Results
In the combined group, VAS and 8-OHdG two days after exercise, CIR two and three days after exercise and LDH from one to three days after exercise were significantly lower than the placebo group. The area under the curve from before exercise to four days later for CIR, LDH, and aldolase was also significantly lower in the combined group than in the placebo group.
Conclusion
A combination of 3.2 g BCAA and 2.0 g taurine, three times a day, for two weeks prior to and three days after exercise may be a useful nutritional strategy for attenuating exercise-induced DOMS and muscle damage.
Subject
Nutrition and Dietetics,Food Science
Reference42 articles.
1. Armstrong RB: Initial events in exercise-induced muscular injury. Med Sci Sports Exerc. 1990, 22: 429-435.
2. Proske U, Morgan DL: Muscle damage from eccentric exercise: mechanism, mechanical signs, adaptation and clinical applications. J Physiol. 2001, 537: 333-345. 10.1111/j.1469-7793.2001.00333.x.
3. Clarkson PM, Ebbeling C: Investigation of serum creatine kinase variability after muscle-damaging exercise. Clin Sci (Lond). 1988, 75: 257-261.
4. Matsumoto K, Koba T, Hamada K, Sakurai M, Higuchi T, Miyata H: Branched-chain amino acid supplementation attenuates muscle soreness, muscle damage and inflammation during an intensive training program. J Sports Med Phys Fitness. 2009, 49: 424-431.
5. Buse MG, Reid SS: Leucine. A possible regulator of protein turnover in muscle. J Clin Invest. 1975, 56: 1250-1261. 10.1172/JCI108201.
Cited by
66 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献