Acute effect of different blood flow restriction protocols on muscle damage

Abstract

The aim of this study is to examine the acute effect of different blood flow restriction (BFR) protocols on muscle damage. Thirty (age 19.77±1.30 years) healthy young men were included in the study. Participants were randomly divided into three groups: Experiment 1 (continuous BFR+ barbell squat, n=10), Experiment 2 (intermittent BFR + barbell squat, n=10), and Control (only barbell squats without BFR, n=10). In 80% of their 1RMs, they performed barbell squat exercises for a total of six sets, with two repetitions in each set and a 3-minute rest interval between sets. For markers of muscle damage creatine kinase (CK), lactate dehydrogenase (LDH), aspartate transaminase (AST), and alanine transaminase (ALT), blood was drawn from the individuals twice before and immediately after the exercise. Analysis of variance in repeated measures (Repeated Measures ANOVA) test was used to analyze the data. In statistical analysis, the level of significance was accepted as p