Cardiorespiratory fitness attenuates age-associated aggregation of white matter hyperintensities in an at-risk cohort

Author:

Vesperman Clayton J.ORCID,Pozorski Vincent,Dougherty Ryan J.,Law Lena L.,Boots Elizabeth,Oh Jennifer M.,Gallagher Catherine L.,Carlsson Cynthia M.,Rowley Howard A.,Ma Yue,Bendlin Barbara B.,Asthana Sanjay,Sager Mark A.,Hermann Bruce P.,Johnson Sterling C.,Cook Dane B.,Okonkwo Ozioma C.

Funder

National Institute on Aging

Clinical and Translational Science Award

Extendicare Foundation

Alzheimer's Association

Helen Bader Foundation

Northwestern Mutual Foundation

Veterans Administration-Geriatric Research Education and Clinical Center of the William S. Middleton Memorial Veterans Hospital, Madison, WI

Publisher

Springer Science and Business Media LLC

Subject

Cognitive Neuroscience,Clinical Neurology,Neurology

Reference50 articles.

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3. Baba R, Nagashima M, Goto M, Nagano Y, Yokota M, Tauchi N, Nishibata K. Oxygen uptake efficiency slope: a new index of cardiorespiratory functional reserve derived from the relation between oxygen uptake and minute ventilation during incremental exercise. J Am Coll Cardiol. 1996;28(6):1567–72.

4. Balke B, Ware RW. An experimental study of physical fitness of Air Force personnel. U S Armed Forces Med J. 1959;10(6):675–88.

5. Bendlin BB, Ries ML, Canu E, Sodhi A, Lazar M, Alexander AL, et al. White matter is altered with parental family history of Alzheimer's disease. Alzheimers Dement. 2010;6(5):394–403. https://doi.org/10.1016/j.jalz.2009.11.003 .

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